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Modeling of an Ion Channel in Its Open Conformation

We have modeled the structure of KirBac1.1 in an open state using as a starting point the structure of KirBac1.1 in its closed conformation (Protein Data Bank 1P7B). To test the validity of the open-state model, molecular dynamics simulations in octane, a lipid bilayer mimetic, were carried out. Sim...

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Detalhes bibliográficos
Main Authors: Domene, Carmen, Doyle, Declan A., Vénien-Bryan, Catherine
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366584/
https://ncbi.nlm.nih.gov/pubmed/15985423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.060855
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