Loop Conformation and Dynamics of the Escherichia coli HPPK Apo-Enzyme and Its Binary Complex with MgATP

Comparison of the crystallographic and NMR structures of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase (HPPK) suggests that the enzyme may undergo significant conformational change upon binding to its first substrate, ATP. Two of the three surface loops (loop 2 and loop 3) accounting for most...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Yang, Rong, Lee, Matthew C., Yan, Honggao, Duan, Yong
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2005
Fag:
Biophysical Theory and Modeling
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366583/
https://ncbi.nlm.nih.gov/pubmed/15821168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.061556
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker