Multiple Loops of the Dihydropyridine Receptor Pore Subunit Are Required for Full-Scale Excitation-Contraction Coupling in Skeletal Muscle

Understanding which cytosolic domains of the dihydropyridine receptor participate in excitation-contraction (EC) coupling is critical to validate current structural models. Here we quantified the contribution to skeletal-type EC coupling of the α1S (Ca(V)1.1) II-III loop when alone or in combination...

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Bibliographic Details
Main Authors: Carbonneau, Leah, Bhattacharya, Dipankar, Sheridan, David C., Coronado, Roberto
Format: Artigo
Language:Inglês
Published: Biophysical Society 2005
Subjects:
Channels, Receptors, and Electrical Signaling
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366522/
https://ncbi.nlm.nih.gov/pubmed/15849247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.056218
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