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The Fast Gating Mechanism in ClC-0 Channels
We investigate and then modify the hypothesis that a glutamate side chain acts as the fast gate in ClC-0 channels. We first create a putative open-state configuration of the prokaryotic ClC Cl(−) channel using its crystallographic structure as a basis. Then, retaining the same pore shape, the prokar...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Biophysical Society
2005
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1366516/ https://ncbi.nlm.nih.gov/pubmed/15863476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.053447 |
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