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The Fast Gating Mechanism in ClC-0 Channels

We investigate and then modify the hypothesis that a glutamate side chain acts as the fast gate in ClC-0 channels. We first create a putative open-state configuration of the prokaryotic ClC Cl(−) channel using its crystallographic structure as a basis. Then, retaining the same pore shape, the prokar...

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Bibliografische gegevens
Hoofdauteurs: Bisset, David, Corry, Ben, Chung, Shin-Ho
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Biophysical Society 2005
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366516/
https://ncbi.nlm.nih.gov/pubmed/15863476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.053447
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