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Inhibition of HLA-DR Assembly, Transport, and Loading by Human Cytomegalovirus Glycoprotein US3: a Novel Mechanism for Evading Major Histocompatibility Complex Class II Antigen Presentation

Human cytomegalovirus (HCMV) establishes persistent lifelong infections and replicates slowly. To withstand robust immunity, HCMV utilizes numerous immune evasion strategies. The HCMV gene cassette encoding US2 to US11 encodes four homologous glycoproteins, US2, US3, US6, and US11, that inhibit the...

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Bibliografiske detaljer
Main Authors: Hegde, Nagendra R., Tomazin, Roman A., Wisner, Todd W., Dunn, Claire, Boname, Jessica M., Lewinsohn, David M., Johnson, David C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC136637/
https://ncbi.nlm.nih.gov/pubmed/12368336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.21.10929-10941.2002
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