Inhibition of HLA-DR Assembly, Transport, and Loading by Human Cytomegalovirus Glycoprotein US3: a Novel Mechanism for Evading Major Histocompatibility Complex Class II Antigen Presentation

Human cytomegalovirus (HCMV) establishes persistent lifelong infections and replicates slowly. To withstand robust immunity, HCMV utilizes numerous immune evasion strategies. The HCMV gene cassette encoding US2 to US11 encodes four homologous glycoproteins, US2, US3, US6, and US11, that inhibit the...

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Main Authors: Hegde, Nagendra R., Tomazin, Roman A., Wisner, Todd W., Dunn, Claire, Boname, Jessica M., Lewinsohn, David M., Johnson, David C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC136637/
https://ncbi.nlm.nih.gov/pubmed/12368336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.21.10929-10941.2002
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