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Efficient Generation and Amplification of High-Capacity Adeno-Associated Virus/Adenovirus Hybrid Vectors

Effective gene therapy is dependent on safe gene delivery vehicles that can achieve efficient transduction and sustained transgene expression. We are developing a hybrid viral vector system that combines in a single particle the large cloning capacity and efficient cell cycle-independent nuclear gen...

Ausführliche Beschreibung

Gespeichert in:
Veröffentlicht in:J Virol
Hauptverfasser: Gonçalves, Manuel A. F. V., van der Velde, Ietje, Janssen, Josephine M., Maassen, Bram T. H., Heemskerk, Evert H., Opstelten, Dirk-Jan E., Knaän-Shanzer, Shoshan, Valerio, Dinko, de Vries, Antoine A. F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2002
Schlagworte:
Gene Therapy
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136621/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12368316/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.21.10734-10744.2002
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