Efficient Generation and Amplification of High-Capacity Adeno-Associated Virus/Adenovirus Hybrid Vectors

Effective gene therapy is dependent on safe gene delivery vehicles that can achieve efficient transduction and sustained transgene expression. We are developing a hybrid viral vector system that combines in a single particle the large cloning capacity and efficient cell cycle-independent nuclear gen...

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Autors principals: Gonçalves, Manuel A. F. V., van der Velde, Ietje, Janssen, Josephine M., Maassen, Bram T. H., Heemskerk, Evert H., Opstelten, Dirk-Jan E., Knaän-Shanzer, Shoshan, Valerio, Dinko, de Vries, Antoine A. F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
Matèries:
Gene Therapy
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC136621/
https://ncbi.nlm.nih.gov/pubmed/12368316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.21.10734-10744.2002
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