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Dendritic Cell-Mediated Viral Transfer to T Cells Is Required for Human Immunodeficiency Virus Type 1 Persistence in the Face of Rapid Cell Turnover

Human immunodeficiency virus type 1 (HIV-1)-infected and activated CD4(+) T cells have short half-lives in vivo (<2 days). We have established an in vitro culture system in which infected T cells are turned over frequently to provide a model system that examines this important facet of in vivo HI...

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Main Authors: Gummuluru, Suryaram, KewalRamani, Vineet N., Emerman, Michael
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2002
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC136613/
https://ncbi.nlm.nih.gov/pubmed/12368311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.21.10692-10701.2002
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