Varicella-Zoster Virus (VZV) ORF17 Protein Induces RNA Cleavage and Is Critical for Replication of VZV at 37(o)C but Not 33(o)C

Varicella-zoster virus (VZV) open reading frame 17 (ORF17) is homologous to herpes simplex virus (HSV) UL41, which encodes the viral host shutoff protein (vhs). HSV vhs induces degradation of mRNA and rapid shutoff of host protein synthesis. An antibody to ORF17 protein detected a 46-kDa protein in...

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Publikašuvnnas:	J Virol
Váldodahkkit:	Sato, Hitoshi, Callanan, Lawrence D., Pesnicak, Lesley, Krogmann, Tammy, Cohen, Jeffrey I.
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	American Society for Microbiology (ASM) 2002
Fáttát:	Replication
Liŋkkat:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136605/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12368344/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.21.11012-11023.2002
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