Varicella-Zoster Virus (VZV) ORF17 Protein Induces RNA Cleavage and Is Critical for Replication of VZV at 37(o)C but Not 33(o)C

Varicella-zoster virus (VZV) open reading frame 17 (ORF17) is homologous to herpes simplex virus (HSV) UL41, which encodes the viral host shutoff protein (vhs). HSV vhs induces degradation of mRNA and rapid shutoff of host protein synthesis. An antibody to ORF17 protein detected a 46-kDa protein in...

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書誌詳細

出版年:	J Virol
主要な著者:	Sato, Hitoshi, Callanan, Lawrence D., Pesnicak, Lesley, Krogmann, Tammy, Cohen, Jeffrey I.
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 2002
主題:	Replication
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136605/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12368344/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.21.11012-11023.2002
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