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Improved Hepatic Gene Transfer by Using an Adeno-Associated Virus Serotype 5 Vector

Adeno-associated viral (AAV) vectors have been shown to direct stable gene transfer and expression in hepatocytes, which makes them attractive tools for treatment of inherited disorders such as hemophilia B. While substantial levels of coagulation factor IX (F.IX) have been achieved using AAV seroty...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Virol
Prif Awduron: Mingozzi, Federico, Schüttrumpf, Jörg, Arruda, Valder R., Liu, Yuhong, Liu, Yi-Lin, High, Katherine A., Xiao, Weidong, Herzog, Roland W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2002
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136579/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12239326/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.20.10497-10502.2002
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