Study of Antigen-Processing Steps Reveals Preferences Explaining Differential Biological Outcomes of Two HLA-A2-Restricted Immunodominant Epitopes from Human Immunodeficiency Virus Type 1

Cytotoxic T-lymphocyte (CTL) responses directed to different human immunodeficiency virus (HIV) epitopes vary in their protective efficacy. In particular, HIV-infected cells are much more sensitive to lysis by anti-Gag/p17(77-85)/HLA-A2 than to that by anti-polymerase/RT(476-484)/HLA-A2 CTL, because...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Cohen, W. M., Bianco, A., Connan, F., Camoin, L., Dalod, M., Lauvau, G., Ferriès, E., Culmann-Penciolelli, B., van Endert, P. M., Briand, J. P., Choppin, J., Guillet, J. G.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136577/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12239297/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.20.10219-10225.2002
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