BCL-2 and BAX Protect Adult Mice from Lethal Sindbis Virus Infection but Do Not Protect Spinal Cord Motor Neurons or Prevent Paralysis

Cellular proteins that regulate apoptotic cell death can modulate the outcome of Sindbis virus (SV) encephalitis in mice. Both endogenous and overexpressed BCL-2 and BAX proteins protect newborn mice from fatal SV infection by blocking apoptosis in infected neurons. To determine the effects of these...

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Detaylı Bibliyografya
Yayımlandı:	J Virol
Asıl Yazarlar:	Kerr, Douglas A., Larsen, Thomas, Cook, Susan H., Fannjiang, Yih-Ru, Choi, Eunkyung, Griffin, Diane E., Hardwick, J. Marie, Irani, David N.
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	American Society for Microbiology (ASM) 2002
Konular:	Pathogenesis and Immunity
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136557/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12239316/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.20.10393-10400.2002
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BCL-2 and BAX Protect Adult Mice from Lethal Sindbis Virus Infection but Do Not Protect Spinal Cord Motor Neurons or Prevent Paralysis

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