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Inhibition of Herpes Simplex Virus Replication by WAY-150138: Assembly of Capsids Depleted of the Portal and Terminase Proteins Involved in DNA Encapsidation

Studies were carried out to examine the mechanism of action of WAY-150138, a member of a novel group of thiourea compounds recently shown to inhibit replication of herpes simplex virus type 1 (HSV-1). Previous studies have shown that the drug acts by preventing DNA encapsidation and that resistant m...

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Bibliografske podrobnosti
izdano v:J Virol
Principais autores: Newcomb, William W., Brown, Jay C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2002
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136520/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12208991/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.19.10084-10088.2002
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