Inhibition of Herpes Simplex Virus Replication by WAY-150138: Assembly of Capsids Depleted of the Portal and Terminase Proteins Involved in DNA Encapsidation

Studies were carried out to examine the mechanism of action of WAY-150138, a member of a novel group of thiourea compounds recently shown to inhibit replication of herpes simplex virus type 1 (HSV-1). Previous studies have shown that the drug acts by preventing DNA encapsidation and that resistant m...

ver descrição completa

Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Newcomb, William W., Brown, Jay C.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Structure and Assembly
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136520/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12208991/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.19.10084-10088.2002
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!