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Decreased Levels of Recent Thymic Emigrants in Peripheral Blood of Simian Immunodeficiency Virus-Infected Macaques Correlate with Alterations within the Thymus

The thymus is responsible for de novo production of CD4(+) and CD8(+) T cells and therefore is essential for T-cell renewal. The goal of this study was to assess the impact of simian immunodeficiency virus (SIV) infection on the production of T cells by the thymus. Levels of recent thymic emigrants...

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Detalhes bibliográficos
Main Authors: Sodora, Donald L., Milush, Jeffrey M., Ware, Felecia, Wozniakowski, Aneta, Montgomery, Lisa, McClure, Harold M., Lackner, Andrew A., Marthas, Marta, Hirsch, Vanessa, Johnson, R. Paul, Douek, Daniel C., Koup, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136511/
https://ncbi.nlm.nih.gov/pubmed/12208974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.19.9981-9990.2002
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