Decreased Levels of Recent Thymic Emigrants in Peripheral Blood of Simian Immunodeficiency Virus-Infected Macaques Correlate with Alterations within the Thymus

The thymus is responsible for de novo production of CD4(+) and CD8(+) T cells and therefore is essential for T-cell renewal. The goal of this study was to assess the impact of simian immunodeficiency virus (SIV) infection on the production of T cells by the thymus. Levels of recent thymic emigrants...

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Détails bibliographiques
Auteurs principaux: Sodora, Donald L., Milush, Jeffrey M., Ware, Felecia, Wozniakowski, Aneta, Montgomery, Lisa, McClure, Harold M., Lackner, Andrew A., Marthas, Marta, Hirsch, Vanessa, Johnson, R. Paul, Douek, Daniel C., Koup, Richard A.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2002
Sujets:
Pathogenesis and Immunity
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC136511/
https://ncbi.nlm.nih.gov/pubmed/12208974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.19.9981-9990.2002
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