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Metabolism of theophylline by cDNA-expressed human cytochromes P-450.

1. Theophylline metabolism was studied using seven human cytochrome P-450 isoforms (CYPs), namely CYP1A1, 1A2, 2A6, 2B6, 2D6, 2E1 and 3A4, and microsomal epoxide hydroxylase (EH), expressed in human B-lymphoblastoid cell lines. 2. At a high theophylline concentration of 10 mM four CYPs (1A1, 1A2, 2D...

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Bibliografski detalji
Glavni autori: Ha, H R, Chen, J, Freiburghaus, A U, Follath, F
Format: Artigo
Jezik:Inglês
Izdano: 1995
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1365010/
https://ncbi.nlm.nih.gov/pubmed/7619675
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