Assessment of arylamine N-acetyltransferase (NAT1) activity in mononuclear leukocytes of cystic fibrosis patients.

The clearance of sulphamethoxazole (SMX), a compound metabolised primarily by the N-acetyltransferase NAT1, is increased in cystic fibrosis (CF) patients. We assessed the activity and kinetic properties of NAT1 in lysates of peripheral blood mononuclear leukocytes (MNL) from CF (n = 17) and control...

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Detalhes bibliográficos
Main Authors: Cribb, A E, Tsui, B, Isbrucker, R, Michael, R T, Gillespie, C T, Brown-Bonomo, J, Barrett, P, Levatte, T, Renton, K W
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1364987/
https://ncbi.nlm.nih.gov/pubmed/7756106
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