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Unexpected Acetylation of Endogenous Aliphatic Amines by Arylamine N‐Acetyltransferase NAT2

N‐Acetyltransferases play critical roles in the deactivation and clearance of xenobiotics, including clinical drugs. NAT2 has been classified as an arylamine N‐acetyltransferase that mainly converts aromatic amines, hydroxylamines, and hydrazines. Herein, we demonstrate that the human arylamine N‐ac...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Angew Chem Int Ed Engl
मुख्य लेखकों: Conway, Louis P., Rendo, Veronica, Correia, Mário S. P., Bergdahl, Ingvar A., Sjöblom, Tobias, Globisch, Daniel
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: John Wiley and Sons Inc. 2020
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7497018/
https://ncbi.nlm.nih.gov/pubmed/32497306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202005915
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