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Caffeine as a metabolic probe: a comparison of the metabolic ratios used to assess CYP1A2 activity.

1. Caffeine is widely used as an in vivo probe for CYP1A2; the distribution/activity of this enzyme is reported to be reflected by metabolic ratios. 2. Several metabolic ratios using different combinations of urinary metabolites have been used to measure CYP1A2, with varying conclusions on its distr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Notarianni, L J, Oliver, S E, Dobrocky, P, Bennett, P N, Silverman, B W
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1995
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1364983/
https://ncbi.nlm.nih.gov/pubmed/7756101
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