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Overexpression of Promyelocytic Leukemia Protein Precludes the Dispersal of ND10 Structures and Has No Effect on Accumulation of Infectious Herpes Simplex Virus 1 or Its Proteins

A key early event in the replication of herpes simplex virus 1 (HSV-1) is the localization of infected-cell protein no. 0 (ICP0) in nuclear structures knows as ND10 or promyelocytic leukemia oncogenic domains (PODs). This is followed by dispersal of ND10 constituents such as the promyelocytic leukem...

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Detalhes bibliográficos
Main Authors: Lopez, Pascal, Jacob, Robert J., Roizman, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136451/
https://ncbi.nlm.nih.gov/pubmed/12186918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.18.9355-9367.2002
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