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Human monoclonal antibodies specific to hepatitis B virus generated in a human/mouse radiation chimera: the Trimera system.

An approach to develop fully human monoclonal antibodies in a human/mouse radiation chimera, the Trimera system, is described. In this system, functional human lymphocytes are engrafted in normal strains of mice which are rendered immuno-incompetent by lethal total body irradiation followed by radio...

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Detalhes bibliográficos
Main Authors: Eren, R, Lubin, I, Terkieltaub, D, Ben-Moshe, O, Zauberman, A, Uhlmann, R, Tzahor, T, Moss, S, Ilan, E, Shouval, D, Galun, E, Daudi, N, Marcus, H, Reisner, Y, Dagan, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1364173/
https://ncbi.nlm.nih.gov/pubmed/9616363
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