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CD4 regulates the efficiency of an endogenous superantigen-induced clonal deletion of TCRV beta 11+ cells in the periphery.

Peripheral T-cell antigen receptor V beta (TCRV beta) repertoire is influenced by clonal deletion both in the thymus and periphery. Developing thymocytes expressing certain TCRV beta are deleted by endogenous superantigens presented on major histocompatibility complex (MHC) molecules in the thymus....

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Bibliographic Details
Main Authors: Kubo, S, Hasegawa, A, Hashimoto, K, Shimizu, C, Kubo, M, Tada, T, Nakayama, T
Format: Artigo
Language:Inglês
Published: 1997
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1364148/
https://ncbi.nlm.nih.gov/pubmed/9497484
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