Modeling Viral Genome Fitness Evolution Associated with Serial Bottleneck Events: Evidence of Stationary States of Fitness

Evolution of fitness values upon replication of viral populations is strongly influenced by the size of the virus population that participates in the infections. While large population passages often result in fitness gains, repeated plaque-to-plaque transfers result in average fitness losses. Here...

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Bibliographic Details

Published in:	J Virol
Main Authors:	Lázaro, Ester, Escarmís, Cristina, Domingo, Esteban, Manrubia, Susanna C.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2002
Subjects:	Recombination and Evolution
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136412/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12163587/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.17.8675-8681.2002
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