Modeling Viral Genome Fitness Evolution Associated with Serial Bottleneck Events: Evidence of Stationary States of Fitness

Evolution of fitness values upon replication of viral populations is strongly influenced by the size of the virus population that participates in the infections. While large population passages often result in fitness gains, repeated plaque-to-plaque transfers result in average fitness losses. Here...

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Détails bibliographiques

Publié dans:	J Virol
Auteurs principaux:	Lázaro, Ester, Escarmís, Cristina, Domingo, Esteban, Manrubia, Susanna C.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2002
Sujets:	Recombination and Evolution
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136412/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12163587/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.17.8675-8681.2002
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