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Nitric oxide produced in the lungs of mice immunized with the radiation-attenuated schistosome vaccine is not the major agent causing challenge parasite elimination.

Mice vaccinated with radiation-attenuated cercariae of Schistosoma mansoni exhibit high levels of protection against a challenge with normal larvae. The immune effector mechanism, which operates against schistosomula in the lungs, requires CD4+ T cells capable of producing interferon-gamma (IFN-gamm...

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Detalhes bibliográficos
Main Authors: Coulson, P S, Smythies, L E, Betts, C, Mabbott, N A, Sternberg, J M, Wei, X G, Liew, F Y, Wilson, R A
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1364106/
https://ncbi.nlm.nih.gov/pubmed/9536119
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