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Replication of Avian Sarcoma Virus In Vivo Requires an Interaction between the Viral RNA and the TψC Loop of the tRNA(Trp) Primer

Reverse transcription in avian sarcoma virus (ASV) initiates from the 3′ end of a tRNA(Trp) primer, which anneals near the 5′ end of the RNA genome. The region around the primer-binding site (PBS) forms an elaborate stem structure composed of the U5-inverted repeat (U5-IR) stem, the U5-leader stem,...

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Bibliographic Details
Published in:J Virol
Main Authors: Morris, Shannon, Johnson, Michael, Stavnezer, Ed, Leis, Jonathan
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2002
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136366/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12097570/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.15.7571-7577.2002
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