Virus-Mediated Transduction of Murine Retina with Adeno-Associated Virus: Effects of Viral Capsid and Genome Size

Gene therapy vectors based on adeno-associated viruses (AAVs) show promise for the treatment of retinal degenerative diseases. In prior work, subretinal injections of AAV2, AAV5, and AAV2 pseudotyped with AAV5 capsids (AAV2/5) showed variable retinal pigmented epithelium (RPE) and photoreceptor cell...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Yang, Grace S., Schmidt, Michael, Yan, Ziying, Lindbloom, Jonathan D., Harding, Thomas C., Donahue, Brian A., Engelhardt, John F., Kotin, Robert, Davidson, Beverly L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
Gene Therapy
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC136354/
https://ncbi.nlm.nih.gov/pubmed/12097579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.15.7651-7660.2002
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky