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Amino Acid Substitutions in the V Domain of Nectin-1 (HveC) That Impair Entry Activity for Herpes Simplex Virus Types 1 and 2 but Not for Pseudorabies Virus or Bovine Herpesvirus 1

The entry of herpes simplex virus (HSV) into cells requires the interaction of viral glycoprotein D (gD) with a cellular gD receptor to trigger the fusion of viral and cellular membranes. Nectin-1, a member of the immunoglobulin superfamily, can serve as a gD receptor for HSV types 1 and 2 (HSV-1 an...

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Bibliographic Details
Main Authors: Martinez, Wanda M., Spear, Patricia G.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC136344/
https://ncbi.nlm.nih.gov/pubmed/12072525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.14.7255-7262.2002
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