Analysis of a Temperature-Sensitive Mutant Rotavirus Indicates that NSP2 Octamers Are the Functional Form of the Protein

Evidence that NSP2 plays a role in packaging and replication comes from studies on tsE(1400), a rotavirus mutant with a temperature-sensitive (ts) lesion in the NSP2 gene. Cells infected with tsE and maintained at nonpermissive temperature contain few replication-assembly factories (viroplasms) or r...

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Hlavní autoři: Taraporewala, Zenobia F., Schuck, Peter, Ramig, Robert F., Silvestri, Lynn, Patton, John T.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
Replication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC136338/
https://ncbi.nlm.nih.gov/pubmed/12072508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.14.7082-7093.2002
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