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Coreceptor Phenotype of Natural Human Immunodeficiency Virus with Nef Deleted Evolves In Vivo, Leading to Increased Virulence

The Sydney Blood Bank Cohort is a group of patients with slowly progressive infection by a human immunodeficiency virus strain containing spontaneous deletions within the nef long terminal repeat region. In 1999, 18 years after the initial infection, one of the members (D36) developed AIDS. In this...

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Published in:J Virol
Main Authors: Jekle, Andreas, Schramm, Birgit, Jayakumar, Prerana, Trautner, Verena, Schols, Dominique, De Clercq, Erik, Mills, John, Crowe, Suzanne M., Goldsmith, Mark A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2002
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136331/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12072497/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.14.6966-6973.2002
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