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Heparin Binds to Murine Leukemia Virus and Inhibits Env-Independent Attachment and Infection

Certain glycosaminoglycans (GAGs), including heparin, inhibit infection by murine leukemia virus (MLV). We now show that this is due to inhibition of virus attachment independent of the interaction between viral envelope proteins (Env) and their cellular receptors. Heparin blocked the binding of bot...

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Detalhes bibliográficos
Main Authors: Walker, Simon J., Pizzato, Massimo, Takeuchi, Yasuhiro, Devereux, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136325/
https://ncbi.nlm.nih.gov/pubmed/12072492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.14.6909-6918.2002
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