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Heparin Binds to Murine Leukemia Virus and Inhibits Env-Independent Attachment and Infection

Certain glycosaminoglycans (GAGs), including heparin, inhibit infection by murine leukemia virus (MLV). We now show that this is due to inhibition of virus attachment independent of the interaction between viral envelope proteins (Env) and their cellular receptors. Heparin blocked the binding of bot...

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Autores principales: Walker, Simon J., Pizzato, Massimo, Takeuchi, Yasuhiro, Devereux, Stephen
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC136325/
https://ncbi.nlm.nih.gov/pubmed/12072492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.14.6909-6918.2002
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