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Disruption of Adherens Junctions Liberates Nectin-1 To Serve as Receptor for Herpes Simplex Virus and Pseudorabies Virus Entry

Nectin-1, a cell adhesion molecule belonging to the immunoglobulin superfamily, can bind to virion glycoprotein D (gD) to mediate entry of herpes simplex viruses (HSV) and pseudorabies virus (PRV). Nectin-1 colocalizes with E-cadherin at adherens junctions in epithelial cells. The disruption of cell...

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Bibliografiske detaljer
Main Authors: Yoon, Miri, Spear, Patricia G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC136315/
https://ncbi.nlm.nih.gov/pubmed/12072519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.14.7203-7208.2002
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