Inefficient Enhancement of Viral Infectivity and CD4 Downregulation by Human Immunodeficiency Virus Type 1 Nef from Japanese Long-Term Nonprogressors

It has been reported that patients infected with nef-defective human immunodeficiency virus type 1 (HIV-1) do not progress to AIDS; however, mutations that abrogate Nef expression are not common in long-term nonprogressors (LTNPs). We postulated that Nef function might be impaired in LTNPs, irrespec...

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Hlavní autoři: Tobiume, Minoru, Takahoko, Mikako, Yamada, Takeshi, Tatsumi, Masashi, Iwamoto, Aikichi, Matsuda, Michiyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC136235/
https://ncbi.nlm.nih.gov/pubmed/12021328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.12.5959-5965.2002
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