Identification of Active-Site Amino Acid Residues in the Chiba Virus 3C-Like Protease

The 3C-like protease of the Chiba virus, a Norwalk-like virus, is one of the chymotrypsin-like proteases. To identify active-site amino acid residues in this protease, 37 charged amino acid residues and a putative nucleophile, Cys139, within the GDCG sequence were individually replaced with Ala in t...

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izdano v:	J Virol
Principais autores:	Someya, Yuichi, Takeda, Naokazu, Miyamura, Tatsuo
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2002
Teme:	Structure and Assembly
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136217/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12021327/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.12.5949-5958.2002
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