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Identification of Active-Site Amino Acid Residues in the Chiba Virus 3C-Like Protease

The 3C-like protease of the Chiba virus, a Norwalk-like virus, is one of the chymotrypsin-like proteases. To identify active-site amino acid residues in this protease, 37 charged amino acid residues and a putative nucleophile, Cys139, within the GDCG sequence were individually replaced with Ala in t...

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Detalhes bibliográficos
Main Authors: Someya, Yuichi, Takeda, Naokazu, Miyamura, Tatsuo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136217/
https://ncbi.nlm.nih.gov/pubmed/12021327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.12.5949-5958.2002
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