A mechanism of AP-1 suppression through interaction of c-Fos with lamin A/C

AP-1 (Activating Protein 1) transcription factor activity is tightly regulated at multiple levels, including dimer formation (i.e., Fos/Jun). Here we show that the intermediate filament protein lamin A/C suppresses AP-1 function through direct interaction with c-Fos, and that both proteins can inter...

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Main Authors: Ivorra, Carmen, Kubicek, Markus, González, José M., Sanz-González, Silvia M., Álvarez-Barrientos, Alberto, O'Connor, José-Enrique, Burke, Brian, Andrés, Vicente
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2006
Assuntos:
Research Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1361702/
https://ncbi.nlm.nih.gov/pubmed/16452503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.349506
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