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Fast regulation of AP-1 activity through interaction of lamin A/C, ERK1/2, and c-Fos at the nuclear envelope

Sequestration of c-Fos at the nuclear envelope (NE) through interaction with A-type lamins suppresses AP-1–dependent transcription. We show here that c-Fos accumulation within the extraction-resistant nuclear fraction (ERNF) and its interaction with lamin A are reduced and enhanced by gain-of and lo...

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Main Authors: González, José María, Navarro-Puche, Ana, Casar, Berta, Crespo, Piero, Andrés, Vicente
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582892/
https://ncbi.nlm.nih.gov/pubmed/19015316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200805049
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