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African Swine Fever Virus IAP-Like Protein Induces the Activation of Nuclear Factor Kappa B

African swine fever virus (ASFV) encodes a homologue of the inhibitor of apoptosis (IAP) that promotes cell survival by controlling the activity of caspase-3. Here we show that ASFV IAP is also able to activate the transcription factor NF-κB. Thus, transient transfection of the viral IAP increases t...

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Bibliografske podrobnosti
Main Authors: Rodríguez, Clara I., Nogal, María L., Carrascosa, Angel L., Salas, María L., Fresno, Manuel, Revilla, Yolanda
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2002
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC136102/
https://ncbi.nlm.nih.gov/pubmed/11907233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.8.3936-3942.2002
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