African Swine Fever Virus IAP Homologue Inhibits Caspase Activation and Promotes Cell Survival in Mammalian Cells

African swine fever virus (ASFV) A224L is a member of the inhibitor of apoptosis protein (IAP) family. We have investigated the antiapoptotic function of the viral IAP both in stably transfected cells and in ASFV-infected cells. A224L was able to substantially inhibit caspase activity and cell death...

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Detalhes bibliográficos
Main Authors: Nogal, María L., González de Buitrago, Gonzalo, Rodríguez, Clara, Cubelos, Beatriz, Carrascosa, Angel L., Salas, María L., Revilla, Yolanda
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC115875/
https://ncbi.nlm.nih.gov/pubmed/11222676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.6.2535-2543.2001
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