Human T-Lymphotropic Virus Type 1 Oncoprotein Tax Promotes S-Phase Entry but Blocks Mitosis

Human T-lymphotropic virus type 1 (HTLV-1) Tax exerts pleiotropic effects on multiple cellular regulatory processes to bring about NF-κB activation, aberrant cell cycle progression, and cell transformation. Here we report that Tax stimulates cellular G(1)/S entry but blocks mitosis. Tax expression i...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Liang, Min-Hui, Geisbert, Thomas, Yao, Yao, Hinrichs, Steven H., Giam, Chou-Zen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136099/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11907241/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.8.4022-4033.2002
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