Human T-Lymphotropic Virus Type 1 Oncoprotein Tax Promotes S-Phase Entry but Blocks Mitosis

Human T-lymphotropic virus type 1 (HTLV-1) Tax exerts pleiotropic effects on multiple cellular regulatory processes to bring about NF-κB activation, aberrant cell cycle progression, and cell transformation. Here we report that Tax stimulates cellular G(1)/S entry but blocks mitosis. Tax expression i...

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Detalhes bibliográficos
Main Authors: Liang, Min-Hui, Geisbert, Thomas, Yao, Yao, Hinrichs, Steven H., Giam, Chou-Zen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136099/
https://ncbi.nlm.nih.gov/pubmed/11907241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.8.4022-4033.2002
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