Selection of RNA Aptamers That Are Specific and High-Affinity Ligands of the Hepatitis C Virus RNA-Dependent RNA Polymerase

In order to find small RNA molecules that are specific and high-affinity ligands of nonstructural 5B (NS5B) polymerase, we screened by SELEX (systematic evolution of ligands by exponential amplification) a structurally constrained RNA library with an NS5BΔC55 enzyme carrying a C-terminal biotinylati...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	J Virol
Päätekijät:	Biroccio, Antonino, Hamm, Jörg, Incitti, Ilario, De Francesco, Raffaele, Tomei, Licia
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	American Society for Microbiology (ASM) 2002
Aiheet:	Replication
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136087/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11907208/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.8.3688-3696.2002
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