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Nur77 is phosphorylated in cells by RSK in response to mitogenic stimulation
Nur77 is a nuclear orphan receptor that is able to activate transcription independently of exogenous ligand, and has also been shown to promote apoptosis on its localization to mitochondria. Phosphorylation of Nur77 on Ser(354) has been suggested to reduce ability of Nur77 to bind DNA; however, the...
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| Huvudupphovsmän: | , , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Portland Press Ltd.
2006
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1360724/ https://ncbi.nlm.nih.gov/pubmed/16223362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050967 |
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