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Extracellular NAD(+) regulates intracellular calcium levels and induces activation of human granulocytes

β-NAD(+)(e) (extracellular β-NAD(+)), present at nanomolar levels in human plasma, has been implicated in the regulation of [Ca(2+)](i) (the intracellular calcium concentration) in various cell types, including blood cells, by means of different mechanisms. Here, we demonstrate that micromolar NAD(+...

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Autors principals: Bruzzone, Santina, Moreschi, Iliana, Guida, Lucrezia, Usai, Cesare, Zocchi, Elena, De Flora, Antonio
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360722/
https://ncbi.nlm.nih.gov/pubmed/16225456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051302
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