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MMP9 from bone marrow-derived cells contributes to survival but not growth of tumor cells in the lung microenvironment
The role of specific stromal-derived MMPs was analyzed in experimental metastasis assays in wildtype and either MMP9, MMP7, or MMP2 null mice. MMP9 null mice showed an 81% reduction in Lewis Lung Carcinoma tumor number, while MMP7 null mice showed a 42% increase in tumor number and there was no diff...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1360653/ https://ncbi.nlm.nih.gov/pubmed/16397239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-05-2502 |
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